Adrenaline powered a tiring Ellie Simmonds into the final of the S6 50 metres freestyle as the 17-year-old was greeted by wild cheers at the Aquatics Centre.
The Walsall-born swimmer has already claimed two titles and two world records in the SM6 200m individual medley and S6 400m freestyle, though she admitted fatigue may prevent her from adding to the haul.
Fifth in the 50m in Beijing, she clocked 36.45 seconds behind Holland's defending champion Mirjam de Koning-Peper, American Victoria Arlen - second in the 400m - and Tanja Groepper of Germany.
The Walsall-born swimmer said: "It's going to be a tough race. The 50m free is my fourth best event but it helps develop my 100 free for later on in the week.
"I am really achy this morning from my 200IM: it was a bit of a killer."
There was disappointment for the Britons in the Olympic Stadium, however, where Shelly Woods bowed out of her second event.
Woods and team-mate Jade Jones both missed out on a place in the final of the T54 800 metres, the latter by an agonising 0.02 seconds and Woods by 0.25secs.
Woods, who was eighth in the 5,000m, came third in her heat with only the top two going through automatically, but insisted she had not expected to make the final, with the marathon on the last day of competition her real gold medal chance.
Jones, the 16-year-old coached by Tanni Grey-Thompson, finished fifth in the fastest heat won by American six-time Paralympic medallist Tatyana McFadden.
Jamie Carter, a 17-year-old mentored by gold medallist David Weir, raised the mood, though, as he edged into the T34 200m final as a fastest loser, coming home fifth in 30.85s.
The only home finalist this morning was the multi-talented sprinter-turned-thrower Beverley Jones, who has a Commonwealth Games 100m medal and plays cricket for Wales.
The 37-year-old, who has cerebral palsy and was competing at her fourth Games, finished seventh in the F37 shot put with a best throw of 9.85m.
Sally Brown, 17, made it into the final of the T46 100m, but Tracey Hinton went out of the T11 class over the same distance.
Peter Norfolk's bid to defend his wheelchair tennis mixed quad singles title ended with defeat against Israel's Shraga Weinberg.
Norfolk, known as the Quadfather, won the opening set 6-3.
But Weinberg fought back to take the second 7-5, as Norfolk's serve faltered resulting in 12 double faults.
Weinberg took the final set 6-0 to book a place in the semi-finals after two hours and 16 minutes.
Norfolk must now hope that he can claim gold in the quad doubles with Andy Lapthorne tomorrow.
Nigel Murray ensured he would end his final Paralympics with a medal after Great Britain's mixed BC1-2 team secured boccia bronze at the ExCel.
The 48-year-old is Britain's most successful boccia player ever, having taken two golds and a silver since making his Games debut in Sydney 12 years ago.
Bouncing back from yesterday's 18-1 semi-final defeat to Thailand, Murray, Daniel Bentley, Zoe Robinson and David Smith topped Portugal 7-5.
However, Peter and Stephen McGuire missed bronze in the BC4 class as they lost 8-2 to Canada.
At Greenwich Park, Sophie Wells and Pinocchio took silver in the freestyle test Grade IV equestrian final, losing out to Michele George and Rainman.
Matthew Skelhon took bronze in the mixed R6-50m rifle prone SH1 shooting final, with Abdulla Sultan Alaryani winning gold for the United Arab Emirates.
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