Morecambe’s Jono Gates exploited a slow-paced Birch Hall pitch, taking 6-36 as Darwen were demolished for just 71.
Only John Cordingley, who battled through 78 balls for an undefeated 23, showed the application needed.
Earlier Ikram Ullah (67) and Andy Armstrong (36) posted 105 for the first wicket and Charles Boucher hit an undefeated 51 to help Morecambe to 195-7.
Gareth Cordingley took two wickets in two balls in a rare high-spot in a dismal Darwen effort, including a first-ball leg before decision against pro Mandla Mashimbyi.
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