A major section of the motorway was closed following a crash in which two people died.
Police were called at 11.18am on Monday following a crash involving a van and a car on the M6 northbound between junctions 39 and 40.
Two people who were in the car were pronounced dead at the scene.
A third person who was in the car, a man, in his forties, was taken to the Cumberland Infirmary in Carlisle after suffering a number of injuries.
A spokesperson for Cumbria police said: "Two men who were in the van did not suffer significant injuries. They were taken to the Cumberland Infirmary.
"The M6 northbound was closed following the crash while emergency services responded to the collision."
Earlier on Monday, drivers heading north along the M6 towards Cumbria and Scotland were being advised the northbound carriageway had been closed following a serious road traffic collision – and is likely to remain closed beyond this evening’s peak travel period.
The northbound carriageway is currently closed from junction 39 at Shap to junction 40 at Penrith.
Following the collision shortly before 12pm on Monday, Cumbria Police launched an incident investigation which is likely to take several hours.
National Highways will then need to inspect the carriageway for any damage and carry out any repairs before the northbound carriageway can reopen.
The southbound carriageway was closed briefly due to smoke from a fire in a vehicle involved in the incident but has since re-opened.
The #M6 northbound between J39 #Shap and J40 #Penrith is closed following a collision and lorry fire. The southbound is blocked while @CumbriaFire deal with the fire. Follow the hollow triangle diversion symbol. For more information click here: https://t.co/ATdUWkahw8 pic.twitter.com/BzaDcqvLGY
— National Highways: North-West (@HighwaysNWEST) February 28, 2022
National Highways traffic officers are at the scene helping to free drivers stuck between junction 39 and the incident; vehicles are being turned around and freed from the motorway at junction 39.
Staff at the North West Regional Operations Centre (NWROC) near Warrington and National Traffic Operations Centre (NTOC) at Birmingham have set electronic signs across the motorway network to warn drivers of the northbound carriageway closure.
A diversion is in place from junction 39 using the parallel A6 but drivers wishing to avoid congestion along the A6 should seek an alternative route or delay their journeys.
Drivers are advised to check traffic conditions before setting out on journeys.
Live traffic information is always available at www.trafficengland.com or from National Highways’ 24-7 customer contact centre at 0300 123 5000.
Updates will also be posted to @HighwaysNWest – National Highways’ regional Twitter feed
Officers are appealing for anyone who witnessed the collision to contact them online at www.cumbria.police.uk/reportit - you can also phone on 101.
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